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Enhancing chemosensitivity to gemcitabine via RNA interference targeting the catalytic subunits of protein kinase CK2 in human pancreatic cancer cells

BACKGROUND: Pancreatic cancer is a complex genetic disorder that is characterized by rapid progression, invasiveness, resistance to treatment and high molecular heterogeneity. Various agents have been used in clinical trials showing only modest improvements with respect to gemcitabine-based chemothe...

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Detalles Bibliográficos
Autores principales:	Kreutzer, Jan N, Ruzzene, Maria, Guerra, Barbara
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931491/ https://www.ncbi.nlm.nih.gov/pubmed/20718998 http://dx.doi.org/10.1186/1471-2407-10-440

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