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In vitro study on the schedule-dependency of the interaction between pemetrexed, gemcitabine and irradiation in non-small cell lung cancer and head and neck cancer cells

BACKGROUND: Based on their different mechanisms of action, non-overlapping side effects and radiosensitising potential, combining the antimetabolites pemetrexed (multitargeted antifolate, MTA) and gemcitabine (2',2'-difluorodeoxycytidine, dFdC) with irradiation (RT) seems promising. This i...

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Detalles Bibliográficos
Autores principales:	Wouters, An, Pauwels, Bea, Lardon, Filip, Pattyn, Greet GO, Lambrechts, Hilde AJ, Baay, Marc, Meijnders, Paul, Vermorken, Jan B
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931492/ https://www.ncbi.nlm.nih.gov/pubmed/20723210 http://dx.doi.org/10.1186/1471-2407-10-441

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