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Deoxysphingoid bases as plasma markers in Diabetes mellitus

BACKGROUND: Sphingoid bases are formed from the precursors L-serine and palmitoyl-CoA-a reaction which is catalyzed by the serine-palmitoyltransferase (SPT). SPT metabolizes, besides palmitoyl-CoA also other acyl-CoAs but shows also variability towards the use of other amino acid substrates. The enz...

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Detalles Bibliográficos
Autores principales: Bertea, Mariana, Rütti, Markus F, Othman, Alaa, Marti-Jaun, Jaqueline, Hersberger, Martin, von Eckardstein, Arnold, Hornemann, Thorsten
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931514/
https://www.ncbi.nlm.nih.gov/pubmed/20712864
http://dx.doi.org/10.1186/1476-511X-9-84