Imbalanced pattern completion vs. separation in cognitive disease: network simulations of synaptic pathologies predict a personalized therapeutics strategy

BACKGROUND: Diverse Mouse genetic models of neurodevelopmental, neuropsychiatric, and neurodegenerative causes of impaired cognition exhibit at least four convergent points of synaptic malfunction: 1) Strength of long-term potentiation (LTP), 2) Strength of long-term depression (LTD), 3) Relative in...

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Detalles Bibliográficos
Autores principales: Hanson, Jesse E, Madison, Daniel V
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931521/
https://www.ncbi.nlm.nih.gov/pubmed/20704756
http://dx.doi.org/10.1186/1471-2202-11-96

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931521/
https://www.ncbi.nlm.nih.gov/pubmed/20704756
http://dx.doi.org/10.1186/1471-2202-11-96

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