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Treatment with a proton pump inhibitor improves glycaemic control in Psammomys obesus, a model of type 2 diabetes
AIMS/HYPOTHESIS: Gastrin has been implicated in islet growth/neogenesis, and proton pump inhibitors (PPIs) have been shown to increase endogenous gastrin levels in animals and humans. Therefore, we investigated the effect of PPIs in a model of type 2 diabetes, Psammomys obesus. METHODS: P. obesus (m...
Autores principales: | Bödvarsdóttir, T. B., Hove, K. D., Gotfredsen, C. F., Pridal, L., Vaag, A., Karlsen, A. E., Petersen, J. S. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931641/ https://www.ncbi.nlm.nih.gov/pubmed/20585936 http://dx.doi.org/10.1007/s00125-010-1825-6 |
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