Cargando…
Prediction and Testing of Biological Networks Underlying Intestinal Cancer
Colorectal cancer progresses through an accumulation of somatic mutations, some of which reside in so-called “driver” genes that provide a growth advantage to the tumor. To identify points of intersection between driver gene pathways, we implemented a network analysis framework using protein interac...
Autores principales: | Patel, Vishal N., Bebek, Gurkan, Mariadason, John M., Wang, Donghai, Augenlicht, Leonard H., Chance, Mark R. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931697/ https://www.ncbi.nlm.nih.gov/pubmed/20824133 http://dx.doi.org/10.1371/journal.pone.0012497 |
Ejemplares similares
-
PETALS: Proteomic Evaluation and Topological Analysis of a mutated Locus' Signaling
por: Bebek, Gurkan, et al.
Publicado: (2010) -
MAGNET: MicroArray Gene expression and Network Evaluation Toolkit
por: Linderman, George C., et al.
Publicado: (2012) -
PathFinder: mining signal transduction pathway segments from protein-protein interaction networks
por: Bebek, Gurkan, et al.
Publicado: (2007) -
Microenvironmental genomic alterations reveal signaling networks for head and neck squamous cell carcinoma
por: Bebek, Gurkan, et al.
Publicado: (2011) -
EOGT enables residual Notch signaling in mouse intestinal cells lacking POFUT1
por: Nauman, Mohd, et al.
Publicado: (2023)