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Gene Knock-Outs of Inositol 1,4,5-Trisphosphate Receptors Types 1 and 2 Result in Perturbation of Cardiogenesis
BACKGROUND: Inositol 1,4,5-trisphosphate receptors (IP(3)R1, 2, and 3) are intracellular Ca(2+) release channels that regulate various vital processes. Although the ryanodine receptor type 2, another type of intracellular Ca(2+) release channel, has been shown to play a role in embryonic cardiomyocy...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931702/ https://www.ncbi.nlm.nih.gov/pubmed/20824138 http://dx.doi.org/10.1371/journal.pone.0012500 |