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Membrane Topology Mapping of the O-Antigen Flippase (Wzx), Polymerase (Wzy), and Ligase (WaaL) from Pseudomonas aeruginosa PAO1 Reveals Novel Domain Architectures

Biosynthesis of B-band lipopolysaccharide (LPS) in Pseudomonas aeruginosa follows the Wzy-dependent pathway, requiring the integral inner membrane proteins Wzx (O-antigen [O-Ag] flippase), Wzy (O-Ag polymerase), and WaaL (O-Ag ligase). For an important first step in deciphering the mechanisms of LPS...

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Detalles Bibliográficos
Autores principales:	Islam, Salim T., Taylor, Véronique L., Qi, Meng, Lam, Joseph S.
Formato:	Texto
Lenguaje:	English
Publicado:	American Society of Microbiology 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2932511/ https://www.ncbi.nlm.nih.gov/pubmed/20824106 http://dx.doi.org/10.1128/mBio.00189-10

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