Cargando…

Surface Co-Expression of Two Different PfEMP1 Antigens on Single Plasmodium falciparum-Infected Erythrocytes Facilitates Binding to ICAM1 and PECAM1

The Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) antigens play a major role in cytoadhesion of infected erythrocytes (IE), antigenic variation, and immunity to malaria. The current consensus on control of variant surface antigen expression is that only one PfEMP1 encoded by one var...

Descripción completa

Detalles Bibliográficos
Autores principales:	Joergensen, Louise, Bengtsson, Dominique C., Bengtsson, Anja, Ronander, Elena, Berger, Sanne S., Turner, Louise, Dalgaard, Michael B., Cham, Gerald K. K., Victor, Michala E., Lavstsen, Thomas, Theander, Thor G., Arnot, David E., Jensen, Anja T. R.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2932717/ https://www.ncbi.nlm.nih.gov/pubmed/20824088 http://dx.doi.org/10.1371/journal.ppat.1001083

Ejemplares similares

Plasmodium falciparum Expressing Domain Cassette 5 Type PfEMP1 (DC5-PfEMP1) Bind PECAM1
por: Berger, Sanne S., et al.
Publicado: (2013)

Insect cells are superior to Escherichia coli in producing malaria proteins inducing IgG targeting PfEMP1 on infected erythrocytes
por: Victor, Michala E, et al.
Publicado: (2010)

A method for visualizing surface-exposed and internal PfEMP1 adhesion antigens in Plasmodium falciparum infected erythrocytes
por: Bengtsson, Dominique, et al.
Publicado: (2008)

The kinetics of antibody binding to Plasmodium falciparum VAR2CSA PfEMP1 antigen and modelling of PfEMP1 antigen packing on the membrane knobs
por: Joergensen, Lars M, et al.
Publicado: (2010)

Mapping the Binding Site of a Cross-Reactive Plasmodium falciparum PfEMP1 Monoclonal Antibody Inhibitory of ICAM-1 Binding
por: Lennartz, Frank, et al.
Publicado: (2015)

Structure-Guided Identification of a Family of Dual Receptor-Binding PfEMP1 that Is Associated with Cerebral Malaria
por: Lennartz, Frank, et al.
Publicado: (2017)

Cerebral Plasmodium falciparum malaria: The role of PfEMP1 in its pathogenesis and immunity, and PfEMP1‐based vaccines to prevent it
por: Jensen, Anja Ramstedt, et al.
Publicado: (2019)

Plasmodium falciparum Associated with Severe Childhood Malaria Preferentially Expresses PfEMP1 Encoded by Group A var Genes
por: Jensen, Anja T.R., et al.
Publicado: (2004)

Differences in PfEMP1s recognized by antibodies from patients with uncomplicated or severe malaria
por: Duffy, Michael F., et al.
Publicado: (2016)

A semi-automated multiplex high-throughput assay for measuring IgG antibodies against Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) domains in small volumes of plasma
por: Cham, Gerald KK, et al.
Publicado: (2008)

Antibodies against PfEMP1, RIFIN, MSP3 and GLURP Are Acquired during Controlled Plasmodium falciparum Malaria Infections in Naïve Volunteers
por: Turner, Louise, et al.
Publicado: (2011)

Structural Conservation Despite Huge Sequence Diversity Allows EPCR Binding by the PfEMP1 Family Implicated in Severe Childhood Malaria
por: Lau, Clinton K.Y., et al.
Publicado: (2015)

Natural and Vaccine-Induced Acquisition of Cross-Reactive IgG-Inhibiting ICAM-1-Specific Binding of a Plasmodium falciparum PfEMP1 Subtype Associated Specifically with Cerebral Malaria
por: Olsen, Rebecca W., et al.
Publicado: (2018)

PfEMP1 A-Type ICAM-1-Binding Domains Are Not Associated with Cerebral Malaria in Beninese Children
por: Joste, V., et al.
Publicado: (2020)

Dissection of the Role of PfEMP1 and ICAM-1 in the Sensing of Plasmodium falciparum-Infected Erythrocytes by Natural Killer Cells
por: Baratin, Myriam, et al.
Publicado: (2007)

Multiple var2csa-Type PfEMP1 Genes Located at Different Chromosomal Loci Occur in Many Plasmodium falciparum Isolates
por: Sander, Adam F., et al.
Publicado: (2009)

Structure-Guided Design of a Synthetic Mimic of an Endothelial Protein C Receptor-Binding PfEMP1 Protein
por: Barber, Natalie M., et al.
Publicado: (2021)

Differential PfEMP1 Expression Is Associated with Cerebral Malaria Pathology
por: Tembo, Dumizulu L., et al.
Publicado: (2014)

Structure-Function-Immunogenicity Studies of PfEMP1 Domain DBL2β(PF11_0521), a Malaria Parasite Ligand for ICAM-1
por: Gullingsrud, Justin, et al.
Publicado: (2013)

Neutrophils impose strong immune pressure against PfEMP1 variants implicated in cerebral malaria
por: Zelter, Tamir, et al.
Publicado: (2022)

Associations between IgG reactivity to Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) antigens and Burkitt lymphoma in Ghana and Uganda case-control studies
por: Derkach, Andriy, et al.
Publicado: (2018)

Plasmodium falciparum EPCR-binding PfEMP1 expression increases with malaria disease severity and is elevated in retinopathy negative cerebral malaria
por: Shabani, Estela, et al.
Publicado: (2017)

PfEMP1-Specific Immunoglobulin G Reactivity Among Beninese Pregnant Women With Sickle Cell Trait
por: Lopez-Perez, Mary, et al.
Publicado: (2021)

Investigating the Host Binding Signature on the Plasmodium falciparum PfEMP1 Protein Family
por: Janes, Joel H., et al.
Publicado: (2011)

Plasma Ang2 and ADAM17 levels are elevated during clinical malaria; Ang2 level correlates with severity and expression of EPCR-binding PfEMP1
por: Petersen, Jens E. V., et al.
Publicado: (2016)

Antigenic cartography of immune responses to Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1)
por: Tuju, James, et al.
Publicado: (2019)

Dynamic association of PfEMP1 and KAHRP in knobs mediates cytoadherence during Plasmodium invasion
por: Ganguly, Akshay Kumar, et al.
Publicado: (2015)

Plasmodium falciparum-Infected Erythrocyte Knob Density Is Linked to the PfEMP1 Variant Expressed
por: Subramani, Ramesh, et al.
Publicado: (2015)

Interaction Analysis of a Plasmodium falciparum PHISTa-like Protein and PfEMP1 Proteins
por: Yang, Baoling, et al.
Publicado: (2020)

Combined Transcriptome and Proteome Profiling for Role of pfEMP1 in Antimalarial Mechanism of Action of Dihydroartemisinin
por: Chen, Lina, et al.
Publicado: (2021)

A Specific PfEMP1 Is Expressed in P. falciparum Sporozoites and Plays a Role in Hepatocyte Infection
por: Zanghì, Gigliola, et al.
Publicado: (2018)

In vitro selection for adhesion of Plasmodium falciparum-infected erythrocytes to ABO antigens does not affect PfEMP1 and RIFIN expression
por: van der Puije, William, et al.
Publicado: (2020)

Plasmodium falciparum Rosetting Epitopes Converge in the SD3-Loop of PfEMP1-DBL1α
por: Angeletti, Davide, et al.
Publicado: (2012)

Correction: Antigenic cartography of immune responses to Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1)
Publicado: (2019)

Using the PfEMP1 Head Structure Binding Motif to Deal a Blow at Severe Malaria
por: Patarroyo, Manuel E., et al.
Publicado: (2014)

Evasion of Immunity to Plasmodium falciparum: Rosettes of Blood Group A Impair Recognition of PfEMP1
por: Moll, Kirsten, et al.
Publicado: (2015)

The role of PfEMP1 as targets of naturally acquired immunity to childhood malaria: prospects for a vaccine
por: BULL, PETER C., et al.
Publicado: (2016)

Functional analysis of monoclonal antibodies against the Plasmodium falciparum PfEMP1-VarO adhesin
por: Guillotte, Micheline, et al.
Publicado: (2016)

From genomic to LC-MS/MS evidence: Analysis of PfEMP1 in Benin malaria cases
por: Kamaliddin, Claire, et al.
Publicado: (2019)

Malian adults maintain serologic responses to virulent PfEMP1s amid seasonal patterns of fluctuation
por: Ventimiglia, Noah T., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_eh02lls9g8eehqbi4fvip5mn87