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NANOG Reporter Cell Lines Generated by Gene Targeting in Human Embryonic Stem Cells
BACKGROUND: Pluripotency and self-renewal of human embryonic stem cells (hESCs) is mediated by a complex interplay between extra- and intracellular signaling pathways, which regulate the expression of pluripotency-specific transcription factors. The homeodomain transcription factor NANOG plays a cen...
Autores principales: | Fischer, Yvonne, Ganic, Elvira, Ameri, Jacqueline, Xian, Xiaojie, Johannesson, Martina, Semb, Henrik |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2932718/ https://www.ncbi.nlm.nih.gov/pubmed/20824089 http://dx.doi.org/10.1371/journal.pone.0012533 |
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