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Intracellular Proton Conductance of the Hepatitis C Virus p7 Protein and Its Contribution to Infectious Virus Production
The hepatitis C virus (HCV) p7 protein is critical for virus production and an attractive antiviral target. p7 is an ion channel when reconstituted in artificial lipid bilayers, but channel function has not been demonstrated in vivo and it is unknown whether p7 channel activity plays a critical role...
Autores principales: | Wozniak, Ann L., Griffin, Stephen, Rowlands, David, Harris, Mark, Yi, MinKyung, Lemon, Stanley M., Weinman, Steven A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2932723/ https://www.ncbi.nlm.nih.gov/pubmed/20824094 http://dx.doi.org/10.1371/journal.ppat.1001087 |
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