Two Genes on A/J Chromosome 18 Are Associated with Susceptibility to Staphylococcus aureus Infection by Combined Microarray and QTL Analyses

Although it has recently been shown that A/J mice are highly susceptible to Staphylococcus aureus sepsis as compared to C57BL/6J, the specific genes responsible for this differential phenotype are unknown. Using chromosome substitution strains (CSS), we found that loci on chromosomes 8, 11, and 18 i...

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Detalles Bibliográficos
Autores principales: Ahn, Sun-Hee, Deshmukh, Hitesh, Johnson, Nicole, Cowell, Lindsay G., Rude, Thomas H., Scott, William K., Nelson, Charlotte L., Zaas, Aimee K., Marchuk, Douglas A., Keum, Sehoon, Lamlertthon, Supaporn, Sharma-Kuinkel, Batu K., Sempowski, Gregory D., Fowler, Vance G.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2932726/
https://www.ncbi.nlm.nih.gov/pubmed/20824097
http://dx.doi.org/10.1371/journal.ppat.1001088

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