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Structural and Mutational Analysis of Functional Differentiation between Synaptotagmins-1 and -7
Synaptotagmins are known to mediate diverse forms of Ca(2+)-triggered exocytosis through their C(2) domains, but the principles underlying functional differentiation among them are unclear. Synaptotagmin-1 functions as a Ca(2+) sensor in neurotransmitter release at central nervous system synapses, b...
Autores principales: | Xue, Mingshan, Craig, Timothy K., Shin, Ok-Ho, Li, Liyi, Brautigam, Chad A., Tomchick, Diana R., Südhof, Thomas C., Rosenmund, Christian, Rizo, Josep |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2932738/ https://www.ncbi.nlm.nih.gov/pubmed/20824061 http://dx.doi.org/10.1371/journal.pone.0012544 |
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