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Identifying Regulators for EAG1 Channels with a Novel Electrophysiology and Tryptophan Fluorescence Based Screen
BACKGROUND: Ether-à-go-go (EAG) channels are expressed throughout the central nervous system and are also crucial regulators of cell cycle and tumor progression. The large intracellular amino- and carboxy- terminal domains of EAG1 each share similarity with known ligand binding motifs in other prote...
Autores principales: | Brelidze, Tinatin I., Carlson, Anne E., Davies, Douglas R., Stewart, Lance J., Zagotta, William N. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2932742/ https://www.ncbi.nlm.nih.gov/pubmed/20824064 http://dx.doi.org/10.1371/journal.pone.0012523 |
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