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Integrin-Linked Kinase Is a Functional Mn(2+)-Dependent Protein Kinase that Regulates Glycogen Synthase Kinase-3β (GSK-3β) Phosphorylation
BACKGROUND: Integrin-linked kinase (ILK) is a highly evolutionarily conserved, multi-domain signaling protein that localizes to focal adhesions, myofilaments and centrosomes where it forms distinct multi-protein complexes to regulate cell adhesion, cell contraction, actin cytoskeletal organization a...
Autores principales: | Maydan, Mykola, McDonald, Paul C., Sanghera, Jasbinder, Yan, Jun, Rallis, Charalampos, Pinchin, Sheena, Hannigan, Gregory E., Foster, Leonard J., Ish-Horowicz, David, Walsh, Michael P., Dedhar, Shoukat |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2932980/ https://www.ncbi.nlm.nih.gov/pubmed/20827300 http://dx.doi.org/10.1371/journal.pone.0012356 |
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