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Dedifferentiation and Proliferation of Mammalian Cardiomyocytes
BACKGROUND: It has long been thought that mammalian cardiomyocytes are terminally-differentiated and unable to proliferate. However, myocytes in more primitive animals such as zebrafish are able to dedifferentiate and proliferate to regenerate amputated cardiac muscle. METHODOLOGY/PRINCIPAL FINDINGS...
Autores principales: | Zhang, Yiqiang, Li, Tao-Sheng, Lee, Shuo-Tsan, Wawrowsky, Kolja A., Cheng, Ke, Galang, Giselle, Malliaras, Konstantinos, Abraham, M. Roselle, Wang, Charles, Marbán, Eduardo |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933247/ https://www.ncbi.nlm.nih.gov/pubmed/20838637 http://dx.doi.org/10.1371/journal.pone.0012559 |
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