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Mutational analysis of an archaeal minichromosome maintenance protein exterior hairpin reveals critical residues for helicase activity and DNA binding

BACKGROUND: The mini-chromosome maintenance protein (MCM) complex is an essential replicative helicase for DNA replication in Archaea and Eukaryotes. While the eukaryotic complex consists of six homologous proteins (MCM2-7), the archaeon Sulfolobus solfataricus has only one MCM protein (ssoMCM), six...

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Detalles Bibliográficos
Autores principales:	Brewster, Aaron S, Slaymaker, Ian M, Afif, Samir A, Chen, Xiaojiang S
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933578/ https://www.ncbi.nlm.nih.gov/pubmed/20716382 http://dx.doi.org/10.1186/1471-2199-11-62

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