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XIAP gene expression and function is regulated by autocrine and paracrine TGF-β signaling
BACKGROUND: X-linked inhibitor of apoptosis protein (XIAP) is often overexpressed in cancer cells, where it plays a key role in survival and also promotes invasiveness. To date however, the extracellular signals and intracellular pathways regulating its expression and activity remain incompletely un...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933620/ https://www.ncbi.nlm.nih.gov/pubmed/20712893 http://dx.doi.org/10.1186/1476-4598-9-216 |