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Depletion of the oncoprotein Bcl-3 induces centrosome amplification and aneuploidy in cancer cells
Bcl-3 is an atypical member of the inhibitor of NF-kappa B family of proteins since it can function as a coactivator of transcription. Although this oncogene was described in leukemia, it is overexpressed in a number of solid tumors as well. The oncogenic potential of Bcl-3 has been associated with...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933622/ https://www.ncbi.nlm.nih.gov/pubmed/20731879 http://dx.doi.org/10.1186/1476-4598-9-223 |