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Rapid method for determination of DNA repair capacity in human peripheral blood lymphocytes amongst smokers

BACKGROUND: DNA repair capacity is an important determinant of susceptibility to cancer. The hOGG1 enzyme is crucial for repairing the 8-oxoguanine lesion that occurs either as a byproduct of oxidative metabolism or as a result of exogenous sources such as exposure to cigarette smoke. It has been pr...

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Detalles Bibliográficos
Autores principales: El-Zein, Randa A, Monroy, Claudia M, Cortes, Andrea, Spitz, Margaret R, Greisinger, Anthony, Etzel, Carol J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933626/
https://www.ncbi.nlm.nih.gov/pubmed/20718982
http://dx.doi.org/10.1186/1471-2407-10-439