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Human mammary fibroblasts stimulate invasion of breast cancer cells in a three-dimensional culture and increase stroma development in mouse xenografts
INTRODUCTION: Tumour phenotype is regulated in a complex fashion as a result of interactions between malignant cells and the tumour stroma. Fibroblasts are the most abundant and perhaps most active part of the tumour stroma. A better understanding of the changes that occur in fibroblasts in response...
Autores principales: | Olsen, Charlotta J, Moreira, José, Lukanidin, Eugene M, Ambartsumian, Noona S |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933628/ https://www.ncbi.nlm.nih.gov/pubmed/20723242 http://dx.doi.org/10.1186/1471-2407-10-444 |
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