miRNAs regulate SIRT1 expression during mouse embryonic stem cell differentiation and in adult mouse tissues

SIRT1 is increasingly recognized as a critical regulator of stress responses, replicative senescence, inflammation, metabolism, and aging. SIRT1 expression is regulated transcriptionally and post-transcriptionally, and its enzymatic activity is controlled by NAD(+) levels and interacting proteins. W...

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Detalles Bibliográficos
Autores principales: Saunders, Laura R., Sharma, Amar Deep, Tawney, Jaime, Nakagawa, Masato, Okita, Keisuke, Yamanaka, Shinya, Willenbring, Holger, Verdin, Eric
Formato: Texto
Lenguaje:English
Publicado: Impact Journals LLC 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933889/
https://www.ncbi.nlm.nih.gov/pubmed/20634564

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