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Differential Dynamics of ATR-Mediated Checkpoint Regulators
The ATR-Chk1 checkpoint pathway is activated by UV-induced DNA lesions and replication stress. Little was known about the spatio and temporal behaviour of the proteins involved, and we, therefore, examined the behaviour of the ATRIP-ATR and Rad9-Rad1-Hus1 putative DNA damage sensor complexes and the...
Autores principales: | Warmerdam, Daniël O., Kanaar, Roland, Smits, Veronique A. J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
SAGE-Hindawi Access to Research
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933903/ https://www.ncbi.nlm.nih.gov/pubmed/20847938 http://dx.doi.org/10.4061/2010/319142 |
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