Cargando…

Metformin increases platelet lactate production by inhibiting mitochondrial function

Detalles Bibliográficos
Autores principales:	Protti, A, Lecchi, A, Fortunato, F, Rosini, F, Artoni, A, Greppi, N, Gjoka, A, Mistraletti, G, Comi, G, Gattinoni, L
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Poster Presentation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2934170/ http://dx.doi.org/10.1186/cc8394

Ejemplares similares

Succinate ameliorates mitochondrial oxygen consumption of metformin-intoxicated human platelets
por: Protti, A, et al.
Publicado: (2013)

Metformin overdose causes platelet mitochondrial dysfunction in humans
por: Protti, Alessandro, et al.
Publicado: (2012)

Platelet mitochondrial dysfunction in critically ill patients: comparison between sepsis and cardiogenic shock
por: Protti, Alessandro, et al.
Publicado: (2015)

Metformin increases skeletal muscle lactate production in pigs: a microdialysis study
por: Protti, A, et al.
Publicado: (2011)

Metformin overdose, but not lactic acidosis per se, inhibits oxygen consumption in pigs
por: Protti, Alessandro, et al.
Publicado: (2012)

Mitochondrial Changes in Platelets Are Not Related to Those in Skeletal Muscle during Human Septic Shock
por: Protti, Alessandro, et al.
Publicado: (2014)

Strain threshold for ventilator-induced lung injury
por: Santini, A, et al.
Publicado: (2011)

Changes in computed tomography and ventilation/perfusion mismatch with positive end-expiratory pressure
por: Karbing, DS, et al.
Publicado: (2014)

0990. Role of amplitude and rate of deformation in ventilator-induced lung injury
por: Protti, A, et al.
Publicado: (2014)

Contribution of red blood cells to the compensation for hypocapnic alkalosis through plasmatic strong ion difference variations
por: Langer, T, et al.
Publicado: (2011)

Dual mode of action of metformin on mitochondrial metabolism
por: Andrzejewski, Sylvia, et al.
Publicado: (2014)

Effect of tidal volume and positive end-expiratory pressure on lung hysteresis of healthy piglets
por: Andreis, DT, et al.
Publicado: (2014)

Sepsis induces platelet mitochondrial uncoupling and a gradual increase in respiratory capacity that is negatively associated with clinical outcome
por: Sjövall, F, et al.
Publicado: (2010)

Effect of extracorporeal CO(2 )removal on respiratory rate in spontaneously breathing patients with chronic obstructive pulmonary disease exacerbation
por: Spinelli, E, et al.
Publicado: (2013)

Dilution with three different solutions: plasmatic effects and quantity and quality of urinary output
por: Langer, T, et al.
Publicado: (2011)

Lactate clearance: the earlier the better?
por: Guiotto, G, et al.
Publicado: (2008)

Can we predict arterial lactate from venous lactate in the emergency department?
por: Mikami, A, et al.
Publicado: (2012)

Continuous urinary electrolyte measurement in a swine model of mechanical ventilation
por: Febres, D, et al.
Publicado: (2010)

Daily assay of procalcitonin, C-reactive protein and IL-6 roles in diagnosis and management of severe sepsis
por: Umbrello, M, et al.
Publicado: (2009)

How early is enough in lactate monitoring?
por: Del Gaudio, S, et al.
Publicado: (2006)

Dexmedetomidine ameliorates gut lactate production and impairment of exogenous lactate clearance in an endotoxic sheep model
por: Hernandez, G, et al.
Publicado: (2015)

Metformin-associated lactic acidosis: three patients surviving after continuous venovenous haemofiltration
por: Barbani, F, et al.
Publicado: (2009)

Non-invasive CPAP with face mask: comparison between different devices
por: Galimberti, A, et al.
Publicado: (2010)

Stressors in the ICU: different perceptions of patients, relatives and staff members
por: Umbrello, M, et al.
Publicado: (2012)

Metformin-associated lactic acidosis: risk factors and prognostic factors
por: Falco, V Di, et al.
Publicado: (2013)

Lower platelet mitochondrial function in severe septic patients than in controls
por: Lorente, L, et al.
Publicado: (2015)

Lactate measurement by the capillary method in shocked patients
por: Collange, O, et al.
Publicado: (2008)

Lactate in the burn patient
por: Herrero, EH, et al.
Publicado: (2015)

Oral melatonin in high-risk critically ill patients: quality of sedative effect
por: Sabbatini, G, et al.
Publicado: (2012)

Adipose tissue lactate clearance but not blood lactate clearance is associated with clinical outcome in severe sepsis or septic shock during the post-resuscitation period
por: Theodorakopoulou, M, et al.
Publicado: (2014)

Delayed assessment of serum lactate in sepsis is associated with an increased mortality rate
por: Arnold, R, et al.
Publicado: (2014)

Melatonin blood values and total antioxidant capacity in critically ill patients
por: D'Amato, LA, et al.
Publicado: (2014)

Lactate in burn patients: biomarker of sepsis and mortality
por: Mokline, A, et al.
Publicado: (2012)

Base excess and lactate as predictors of mortality in medical ICU patients
por: Azevedo, L, et al.
Publicado: (2004)

ECMO in nonintubated patients as a bridge to lung transplant: our experience
por: Chierichetti, M, et al.
Publicado: (2012)

How well does increased lactate differentiate between ITU survivors and nonsurvivors?
por: Hubble, S, et al.
Publicado: (2004)

P-9 Construction of a database for a nation-wide Italian collaborative network of mitochondrial diseases
por: Mancuso, M., et al.
Publicado: (2011)

Focus group in Multiple Sclerosis as a tool to increase active patient involvement. A preliminary experience
por: Sgoifo, Annalisa, et al.
Publicado: (2015)

Monitoring of lactate and base deficit: what is their role in the predictive outcome of severe trauma?
por: Azan, G, et al.
Publicado: (2006)

Intrathecal lactate to predict spinal cord ischemia in major abdominal surgery
por: Landoni, G, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_kifbe3csiec2n7sci0277j7kup