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A Novel Pleckstrin Homology Domain-containing Protein Enhances Insulin-stimulated Akt Phosphorylation and GLUT4 Translocation in Adipocytes
Protein kinase B/Akt protein kinases control an array of diverse functions, including cell growth, survival, proliferation, and metabolism. We report here the identification of pleckstrin homology-like domain family B member 1 (PHLDB1) as an insulin-responsive protein that enhances Akt activation. P...
Autores principales: | Zhou, Qiong L., Jiang, Zhen Y., Mabardy, Allan S., Del Campo, Claudia M., Lambright, David G., Holik, John, Fogarty, Kevin E., Straubhaar, Juerg, Nicoloro, Sarah, Chawla, Anil, Czech, Michael P. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2934625/ https://www.ncbi.nlm.nih.gov/pubmed/20587420 http://dx.doi.org/10.1074/jbc.M110.146886 |
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