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Exoresection and Endoresection for Uveal Melanoma

Surgical resection of uveal melanomas is an alternative eye-salvaging approach to the more commonly used irradiation techniques. There are two surgical resection techniques: Transscleral resection or “Exoresection” via a partial lamellar sclerouvectomy and “Endoresection” via a pars plana vitrectomy...

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Detalles Bibliográficos
Autores principales: Gündüz, Kaan, Bechrakis, Nikolaos E.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2934712/
https://www.ncbi.nlm.nih.gov/pubmed/20844676
http://dx.doi.org/10.4103/0974-9233.65494
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author Gündüz, Kaan
Bechrakis, Nikolaos E.
author_facet Gündüz, Kaan
Bechrakis, Nikolaos E.
author_sort Gündüz, Kaan
collection PubMed
description Surgical resection of uveal melanomas is an alternative eye-salvaging approach to the more commonly used irradiation techniques. There are two surgical resection techniques: Transscleral resection or “Exoresection” via a partial lamellar sclerouvectomy and “Endoresection” via a pars plana vitrectomy. While exoresection is more applicable to anteriorly located tumors with ciliary body and/or iris involvement, endoresection is more suitable for posteriorly located tumor without ciliary body involvement. Both approaches are suitable for large tumors with >8 mm in thickness. In general, eyes containing these large tumors have a very dismal prognosis regarding long-term visual function, eye retention, and irradiation-induced side effects. By removing the tumor burden from the eye, histopathologic and cytogenetic information of the tumor is available and complications associated with the so-called toxic tumor syndrome are avoided. However, both types of surgical resection are challenging surgical procedures, bearing the risk of early and late postoperative complications.
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spelling pubmed-29347122010-09-15 Exoresection and Endoresection for Uveal Melanoma Gündüz, Kaan Bechrakis, Nikolaos E. Middle East Afr J Ophthalmol Symposium – Oncology Update Surgical resection of uveal melanomas is an alternative eye-salvaging approach to the more commonly used irradiation techniques. There are two surgical resection techniques: Transscleral resection or “Exoresection” via a partial lamellar sclerouvectomy and “Endoresection” via a pars plana vitrectomy. While exoresection is more applicable to anteriorly located tumors with ciliary body and/or iris involvement, endoresection is more suitable for posteriorly located tumor without ciliary body involvement. Both approaches are suitable for large tumors with >8 mm in thickness. In general, eyes containing these large tumors have a very dismal prognosis regarding long-term visual function, eye retention, and irradiation-induced side effects. By removing the tumor burden from the eye, histopathologic and cytogenetic information of the tumor is available and complications associated with the so-called toxic tumor syndrome are avoided. However, both types of surgical resection are challenging surgical procedures, bearing the risk of early and late postoperative complications. Medknow Publications 2010 /pmc/articles/PMC2934712/ /pubmed/20844676 http://dx.doi.org/10.4103/0974-9233.65494 Text en © Middle East African Journal of Ophthalmology http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Symposium – Oncology Update
Gündüz, Kaan
Bechrakis, Nikolaos E.
Exoresection and Endoresection for Uveal Melanoma
title Exoresection and Endoresection for Uveal Melanoma
title_full Exoresection and Endoresection for Uveal Melanoma
title_fullStr Exoresection and Endoresection for Uveal Melanoma
title_full_unstemmed Exoresection and Endoresection for Uveal Melanoma
title_short Exoresection and Endoresection for Uveal Melanoma
title_sort exoresection and endoresection for uveal melanoma
topic Symposium – Oncology Update
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2934712/
https://www.ncbi.nlm.nih.gov/pubmed/20844676
http://dx.doi.org/10.4103/0974-9233.65494
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