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Hyperphosphorylated FAK Delocalizes from Focal Adhesions to Membrane Ruffles

Cell adhesion and migration are key determinants in tumor metastasis. Adherence of tumor cell to the extracellular matrix is mediated via integrin containing focal adhesions (FAs). Binding of integrins to ECM triggers phosphorylation of two major components of FAs, focal adhesion kinase (FAK) and Sr...

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Detalles Bibliográficos
Autores principales:	Hamadi, Abdelkader, Deramaudt, Therese B., Takeda, Kenneth, Rondé, Philippe
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2934852/ https://www.ncbi.nlm.nih.gov/pubmed/20847951 http://dx.doi.org/10.1155/2010/932803

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