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Role of Topoisomerase IIβ in DNA Damage Response following IR and Etoposide

The role of topoisomerase IIβ was investigated in cell lines exposed to two DNA damaging agents, ionising radiation (IR) or etoposide, a drug which acts on topoisomerase II. The appearance and resolution of γH2AX foci in murine embryonic fibroblast cell lines, wild type and null for DNA topoisomeras...

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Detalles Bibliográficos
Autores principales:	Sunter, Nicola J., Cowell, Ian G., Willmore, Elaine, Watters, Gary P., Austin, Caroline A.
Formato:	Texto
Lenguaje:	English
Publicado:	SAGE-Hindawi Access to Research 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2935090/ https://www.ncbi.nlm.nih.gov/pubmed/20847952 http://dx.doi.org/10.4061/2010/710589

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