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AICD Overexpression in Neuro 2A Cells Regulates Expression of PTCH1 and TRPC5
Amyloid precursor protein (APP), implicated in Alzheimer's disease, is a transmembrane protein of undetermined function. APP is cleaved by gamma-secretase that releases the APP intracellular domain (AICD) in the cytoplasm. In vitro and in vivo studies have implicated the role of AICD in cell si...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
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SAGE-Hindawi Access to Research
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2935165/ https://www.ncbi.nlm.nih.gov/pubmed/20827383 http://dx.doi.org/10.4061/2011/239453 |