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Decreased Levels of Bisecting GlcNAc Glycoforms of IgG Are Associated with Human Longevity

BACKGROUND: Markers for longevity that reflect the health condition and predict healthy aging are extremely scarce. Such markers are, however, valuable in aging research. It has been shown previously that the N-glycosylation pattern of human immunoglobulin G (IgG) is age-dependent. Here we investiga...

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Detalles Bibliográficos
Autores principales: Ruhaak, L. Renee, Uh, Hae-Won, Beekman, Marian, Koeleman, Carolien A. M., Hokke, Cornelis H., Westendorp, Rudi G. J., Wuhrer, Manfred, Houwing-Duistermaat, Jeanine J., Slagboom, P. Eline, Deelder, André M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2935362/
https://www.ncbi.nlm.nih.gov/pubmed/20830288
http://dx.doi.org/10.1371/journal.pone.0012566