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Direct Detection of Diverse Metabolic Changes in Virally Transformed and Tax-Expressing Cells by Mass Spectrometry

BACKGROUND: Viral transformation of a cell starts at the genetic level, followed by changes in the proteome and the metabolome of the host. There is limited information on the broad metabolic changes in HTLV transformed cells. METHODS AND PRINCIPAL FINDINGS: Here, we report the detection of key chan...

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Detalles Bibliográficos
Autores principales: Sripadi, Prabhakar, Shrestha, Bindesh, Easley, Rebecca L., Carpio, Lawrence, Kehn-Hall, Kylene, Chevalier, Sebastien, Mahieux, Renaud, Kashanchi, Fatah, Vertes, Akos
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2935367/
https://www.ncbi.nlm.nih.gov/pubmed/20830293
http://dx.doi.org/10.1371/journal.pone.0012590