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Long-Term IGF-I Exposure Decreases Autophagy and Cell Viability
A reduction in IGF-I signaling has been found to increase lifespan in multiple organisms despite the fact that IGF-I is a trophic factor for many cell types and has been found to have protective effects against multiple forms of damage in acute settings. The increase in longevity seen in response to...
Autores principales: | , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2935370/ https://www.ncbi.nlm.nih.gov/pubmed/20830296 http://dx.doi.org/10.1371/journal.pone.0012592 |