Role of Rac1 GTPase in NADPH Oxidase Activation and Cognitive Impairment Following Cerebral Ischemia in the Rat

BACKGROUND: Recent work by our laboratory and others has implicated NADPH oxidase as having an important role in reactive oxygen species (ROS) generation and neuronal damage following cerebral ischemia, although the mechanisms controlling NADPH oxidase in the brain remain poorly understood. The purp...

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Detalles Bibliográficos
Autores principales: Raz, Limor, Zhang, Quan-Guang, Zhou, Cai-feng, Han, Dong, Gulati, Priya, Yang, Li-cai, Yang, Fang, Wang, Rui-min, Brann, Darrell W.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2935374/
https://www.ncbi.nlm.nih.gov/pubmed/20830300
http://dx.doi.org/10.1371/journal.pone.0012606

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