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Detecting host factors involved in virus infection by observing the clustering of infected cells in siRNA screening images

Motivation: Detecting human proteins that are involved in virus entry and replication is facilitated by modern high-throughput RNAi screening technology. However, hit lists from different laboratories have shown only little consistency. This may be caused by not only experimental discrepancies, but...

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Detalles Bibliográficos
Autores principales: Suratanee, Apichat, Rebhan, Ilka, Matula, Petr, Kumar, Anil, Kaderali, Lars, Rohr, Karl, Bartenschlager, Ralf, Eils, Roland, König, Rainer
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2935410/
https://www.ncbi.nlm.nih.gov/pubmed/20823335
http://dx.doi.org/10.1093/bioinformatics/btq398