RefProtDom: a protein database with improved domain boundaries and homology relationships

Summary: RefProtDom provides a set of divergent query domains, originally selected from Pfam, and full-length proteins containing their homologous domains, with diverse architectures, for evaluating pair-wise and iterative sequence similarity searches. Pfam homology and domain boundary annotations i...

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Detalles Bibliográficos
Autores principales: Gonzalez, Mileidy W., Pearson, William R.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Applications Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2935417/
https://www.ncbi.nlm.nih.gov/pubmed/20693322
http://dx.doi.org/10.1093/bioinformatics/btq426
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author Gonzalez, Mileidy W.
Pearson, William R.
author_facet Gonzalez, Mileidy W.
Pearson, William R.
author_sort Gonzalez, Mileidy W.
collection PubMed
description Summary: RefProtDom provides a set of divergent query domains, originally selected from Pfam, and full-length proteins containing their homologous domains, with diverse architectures, for evaluating pair-wise and iterative sequence similarity searches. Pfam homology and domain boundary annotations in the target library were supplemented using local and semi-global searches, PSI-BLAST searches, and SCOP and CATH classifications. Availability: RefProtDom is available from http://faculty.virginia.edu/wrpearson/fasta/PUBS/gonzalez09a Contact: miledywgonzalez@gmail.com; pearson@virginia.edu
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spelling pubmed-29354172010-09-08 RefProtDom: a protein database with improved domain boundaries and homology relationships Gonzalez, Mileidy W. Pearson, William R. Bioinformatics Applications Note Summary: RefProtDom provides a set of divergent query domains, originally selected from Pfam, and full-length proteins containing their homologous domains, with diverse architectures, for evaluating pair-wise and iterative sequence similarity searches. Pfam homology and domain boundary annotations in the target library were supplemented using local and semi-global searches, PSI-BLAST searches, and SCOP and CATH classifications. Availability: RefProtDom is available from http://faculty.virginia.edu/wrpearson/fasta/PUBS/gonzalez09a Contact: miledywgonzalez@gmail.com; pearson@virginia.edu Oxford University Press 2010-09-15 2010-08-06 /pmc/articles/PMC2935417/ /pubmed/20693322 http://dx.doi.org/10.1093/bioinformatics/btq426 Text en © The Author(s) 2010. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/2.0/uk/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Applications Note
Gonzalez, Mileidy W.
Pearson, William R.
RefProtDom: a protein database with improved domain boundaries and homology relationships
title RefProtDom: a protein database with improved domain boundaries and homology relationships
title_full RefProtDom: a protein database with improved domain boundaries and homology relationships
title_fullStr RefProtDom: a protein database with improved domain boundaries and homology relationships
title_full_unstemmed RefProtDom: a protein database with improved domain boundaries and homology relationships
title_short RefProtDom: a protein database with improved domain boundaries and homology relationships
title_sort refprotdom: a protein database with improved domain boundaries and homology relationships
topic Applications Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2935417/
https://www.ncbi.nlm.nih.gov/pubmed/20693322
http://dx.doi.org/10.1093/bioinformatics/btq426
work_keys_str_mv AT gonzalezmileidyw refprotdomaproteindatabasewithimproveddomainboundariesandhomologyrelationships
AT pearsonwilliamr refprotdomaproteindatabasewithimproveddomainboundariesandhomologyrelationships

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