Inhibition of Antiapoptotic BCL-XL, BCL-2, and MCL-1 Proteins by Small Molecule Mimetics

Informatics and computational design methods were used to create new molecules that could potentially bind antiapoptotic proteins, thus promoting death of cancer cells. Apoptosis is a cellular process that leads to the death of damaged cells. Its malfunction can cause cancer and poor response to con...

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Detalles Bibliográficos
Autores principales: Dalafave, D.S., Prisco, G.
Formato: Texto
Lenguaje:English
Publicado: Libertas Academica 2010
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2935820/
https://www.ncbi.nlm.nih.gov/pubmed/20838611

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2935820/
https://www.ncbi.nlm.nih.gov/pubmed/20838611

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