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Mitochondrial import of PKCε is mediated by HSP90: a role in cardioprotection from ischaemia and reperfusion injury

AIMS: Protein kinase C epsilon (PKCε) is critical for cardiac protection from ischaemia and reperfusion (IR) injury. PKCε substrates that mediate cytoprotection reside in the mitochondria. However, the mechanism enabling mitochondrial translocation and import of PKCε to enable phosphorylation of the...

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Detalles Bibliográficos
Autores principales:	Budas, Grant R., Churchill, Eric N., Disatnik, Marie-Hélène, Sun, Lihan, Mochly-Rosen, Daria
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2010
Materias:	Original Articles: Focus on Mitochondria in Cardiac Disease
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936125/ https://www.ncbi.nlm.nih.gov/pubmed/20558438 http://dx.doi.org/10.1093/cvr/cvq154

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