Cargando…
Generation of a panel of antibodies against proteins encoded on human chromosome 21
BACKGROUND: Down syndrome (DS) is caused by trisomy of all or part of chromosome 21. To further understanding of DS we are working with a mouse model, the Tc1 mouse, which carries most of human chromosome 21 in addition to the normal mouse chromosome complement. This mouse is a model for human DS an...
Autores principales: | Wiseman, Frances K, Sheppard, Olivia, Linehan, Jacqueline M, Brandner, Sebastian, Tybulewicz, Victor LJ, Fisher, Elizabeth MC |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936279/ https://www.ncbi.nlm.nih.gov/pubmed/20727138 http://dx.doi.org/10.1186/1477-5751-9-7 |
Ejemplares similares
-
Down syndrome and the molecular pathogenesis resulting from trisomy of human chromosome 21
por: Ruparelia, Aarti, et al.
Publicado: (2010) -
Altered regulation of tau phosphorylation in a mouse model of down syndrome aging
por: Sheppard, Olivia, et al.
Publicado: (2012) -
An additional human chromosome 21 causes suppression of neural fate of pluripotent mouse embryonic stem cells in a teratoma model
por: Mensah, Afua, et al.
Publicado: (2007) -
Mouse Models of Aneuploidy
por: Sheppard, Olivia, et al.
Publicado: (2012) -
Tc1 mouse model of trisomy-21 dissociates properties of short- and long-term recognition memory
por: Hall, Jessica H., et al.
Publicado: (2016)