Cargando…

Role of positron emission tomography-computed tomography in bronchial mucoepidermoid carcinomas: a case series and review of the literature

INTRODUCTION: Mucoepidermoid carcinoma of the tracheobronchial tree is rare. Such tumors usually present with signs and symptoms of bronchial obstruction. Histologically, they can be classified as high-grade or low-grade tumors. Experience of imaging these tumors with (18)fluorodeoxyglucose positron...

Descripción completa

Detalles Bibliográficos
Autores principales: Jindal, Tarun, Kumar, Arvind, Kumar, Rakesh, Dutta, Roman, Meena, Monika
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936317/
https://www.ncbi.nlm.nih.gov/pubmed/20723235
http://dx.doi.org/10.1186/1752-1947-4-277
_version_ 1782186466862956544
author Jindal, Tarun
Kumar, Arvind
Kumar, Rakesh
Dutta, Roman
Meena, Monika
author_facet Jindal, Tarun
Kumar, Arvind
Kumar, Rakesh
Dutta, Roman
Meena, Monika
author_sort Jindal, Tarun
collection PubMed
description INTRODUCTION: Mucoepidermoid carcinoma of the tracheobronchial tree is rare. Such tumors usually present with signs and symptoms of bronchial obstruction. Histologically, they can be classified as high-grade or low-grade tumors. Experience of imaging these tumors with (18)fluorodeoxyglucose positron emission tomography-computed tomography ((18)F-FDG PET-CT) is limited. We present three cases of this rare tumor, describe the functional imaging results, and review the available literature. CASE PRESENTATION: Three Caucasian patients, two men (21 and 24 years of age) and one woman (14 years of age), with bronchial masses were evaluated by us. All three patients were symptomatic, and underwent a thorough clinical examination, bronchoscopy and biopsy, plain computed tomography, (18)F-FDG PET-CT and (68)Gallium 1,4,7,10-Tetraazacyclododecane-N(I),N(II),N(III),N(IIII),- tetra acetic acid (D) - Phel(1)-Tyr(3)-octreotide positron emission tomography-computed tomography ((68)Ga-DOTATOC PET-CT). (18)F-FDG PET-CT revealed mild uptake in all three patients, whereas (68)Ga-DOTATOC PET-CT revealed no significant uptake in any patient, making carcinoid tumor unlikely. Results of histopathological examination were consistent with low-grade mucoepidermoid carcinoma in all patients. CONCLUSION: Our study reveals that functional imaging may be helpful in the initial investigation of patients with mucoepidermoid carcinoma. (18)F-FDG PET-CT may have a prognostic relevance by predicting the histopathologic differentiation of the tumor.
format Text
id pubmed-2936317
institution National Center for Biotechnology Information
language English
publishDate 2010
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-29363172010-09-10 Role of positron emission tomography-computed tomography in bronchial mucoepidermoid carcinomas: a case series and review of the literature Jindal, Tarun Kumar, Arvind Kumar, Rakesh Dutta, Roman Meena, Monika J Med Case Reports Case Report INTRODUCTION: Mucoepidermoid carcinoma of the tracheobronchial tree is rare. Such tumors usually present with signs and symptoms of bronchial obstruction. Histologically, they can be classified as high-grade or low-grade tumors. Experience of imaging these tumors with (18)fluorodeoxyglucose positron emission tomography-computed tomography ((18)F-FDG PET-CT) is limited. We present three cases of this rare tumor, describe the functional imaging results, and review the available literature. CASE PRESENTATION: Three Caucasian patients, two men (21 and 24 years of age) and one woman (14 years of age), with bronchial masses were evaluated by us. All three patients were symptomatic, and underwent a thorough clinical examination, bronchoscopy and biopsy, plain computed tomography, (18)F-FDG PET-CT and (68)Gallium 1,4,7,10-Tetraazacyclododecane-N(I),N(II),N(III),N(IIII),- tetra acetic acid (D) - Phel(1)-Tyr(3)-octreotide positron emission tomography-computed tomography ((68)Ga-DOTATOC PET-CT). (18)F-FDG PET-CT revealed mild uptake in all three patients, whereas (68)Ga-DOTATOC PET-CT revealed no significant uptake in any patient, making carcinoid tumor unlikely. Results of histopathological examination were consistent with low-grade mucoepidermoid carcinoma in all patients. CONCLUSION: Our study reveals that functional imaging may be helpful in the initial investigation of patients with mucoepidermoid carcinoma. (18)F-FDG PET-CT may have a prognostic relevance by predicting the histopathologic differentiation of the tumor. BioMed Central 2010-08-19 /pmc/articles/PMC2936317/ /pubmed/20723235 http://dx.doi.org/10.1186/1752-1947-4-277 Text en Copyright ©2010 Jindal et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Jindal, Tarun
Kumar, Arvind
Kumar, Rakesh
Dutta, Roman
Meena, Monika
Role of positron emission tomography-computed tomography in bronchial mucoepidermoid carcinomas: a case series and review of the literature
title Role of positron emission tomography-computed tomography in bronchial mucoepidermoid carcinomas: a case series and review of the literature
title_full Role of positron emission tomography-computed tomography in bronchial mucoepidermoid carcinomas: a case series and review of the literature
title_fullStr Role of positron emission tomography-computed tomography in bronchial mucoepidermoid carcinomas: a case series and review of the literature
title_full_unstemmed Role of positron emission tomography-computed tomography in bronchial mucoepidermoid carcinomas: a case series and review of the literature
title_short Role of positron emission tomography-computed tomography in bronchial mucoepidermoid carcinomas: a case series and review of the literature
title_sort role of positron emission tomography-computed tomography in bronchial mucoepidermoid carcinomas: a case series and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936317/
https://www.ncbi.nlm.nih.gov/pubmed/20723235
http://dx.doi.org/10.1186/1752-1947-4-277
work_keys_str_mv AT jindaltarun roleofpositronemissiontomographycomputedtomographyinbronchialmucoepidermoidcarcinomasacaseseriesandreviewoftheliterature
AT kumararvind roleofpositronemissiontomographycomputedtomographyinbronchialmucoepidermoidcarcinomasacaseseriesandreviewoftheliterature
AT kumarrakesh roleofpositronemissiontomographycomputedtomographyinbronchialmucoepidermoidcarcinomasacaseseriesandreviewoftheliterature
AT duttaroman roleofpositronemissiontomographycomputedtomographyinbronchialmucoepidermoidcarcinomasacaseseriesandreviewoftheliterature
AT meenamonika roleofpositronemissiontomographycomputedtomographyinbronchialmucoepidermoidcarcinomasacaseseriesandreviewoftheliterature