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Role of positron emission tomography-computed tomography in bronchial mucoepidermoid carcinomas: a case series and review of the literature
INTRODUCTION: Mucoepidermoid carcinoma of the tracheobronchial tree is rare. Such tumors usually present with signs and symptoms of bronchial obstruction. Histologically, they can be classified as high-grade or low-grade tumors. Experience of imaging these tumors with (18)fluorodeoxyglucose positron...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936317/ https://www.ncbi.nlm.nih.gov/pubmed/20723235 http://dx.doi.org/10.1186/1752-1947-4-277 |
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author | Jindal, Tarun Kumar, Arvind Kumar, Rakesh Dutta, Roman Meena, Monika |
author_facet | Jindal, Tarun Kumar, Arvind Kumar, Rakesh Dutta, Roman Meena, Monika |
author_sort | Jindal, Tarun |
collection | PubMed |
description | INTRODUCTION: Mucoepidermoid carcinoma of the tracheobronchial tree is rare. Such tumors usually present with signs and symptoms of bronchial obstruction. Histologically, they can be classified as high-grade or low-grade tumors. Experience of imaging these tumors with (18)fluorodeoxyglucose positron emission tomography-computed tomography ((18)F-FDG PET-CT) is limited. We present three cases of this rare tumor, describe the functional imaging results, and review the available literature. CASE PRESENTATION: Three Caucasian patients, two men (21 and 24 years of age) and one woman (14 years of age), with bronchial masses were evaluated by us. All three patients were symptomatic, and underwent a thorough clinical examination, bronchoscopy and biopsy, plain computed tomography, (18)F-FDG PET-CT and (68)Gallium 1,4,7,10-Tetraazacyclododecane-N(I),N(II),N(III),N(IIII),- tetra acetic acid (D) - Phel(1)-Tyr(3)-octreotide positron emission tomography-computed tomography ((68)Ga-DOTATOC PET-CT). (18)F-FDG PET-CT revealed mild uptake in all three patients, whereas (68)Ga-DOTATOC PET-CT revealed no significant uptake in any patient, making carcinoid tumor unlikely. Results of histopathological examination were consistent with low-grade mucoepidermoid carcinoma in all patients. CONCLUSION: Our study reveals that functional imaging may be helpful in the initial investigation of patients with mucoepidermoid carcinoma. (18)F-FDG PET-CT may have a prognostic relevance by predicting the histopathologic differentiation of the tumor. |
format | Text |
id | pubmed-2936317 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-29363172010-09-10 Role of positron emission tomography-computed tomography in bronchial mucoepidermoid carcinomas: a case series and review of the literature Jindal, Tarun Kumar, Arvind Kumar, Rakesh Dutta, Roman Meena, Monika J Med Case Reports Case Report INTRODUCTION: Mucoepidermoid carcinoma of the tracheobronchial tree is rare. Such tumors usually present with signs and symptoms of bronchial obstruction. Histologically, they can be classified as high-grade or low-grade tumors. Experience of imaging these tumors with (18)fluorodeoxyglucose positron emission tomography-computed tomography ((18)F-FDG PET-CT) is limited. We present three cases of this rare tumor, describe the functional imaging results, and review the available literature. CASE PRESENTATION: Three Caucasian patients, two men (21 and 24 years of age) and one woman (14 years of age), with bronchial masses were evaluated by us. All three patients were symptomatic, and underwent a thorough clinical examination, bronchoscopy and biopsy, plain computed tomography, (18)F-FDG PET-CT and (68)Gallium 1,4,7,10-Tetraazacyclododecane-N(I),N(II),N(III),N(IIII),- tetra acetic acid (D) - Phel(1)-Tyr(3)-octreotide positron emission tomography-computed tomography ((68)Ga-DOTATOC PET-CT). (18)F-FDG PET-CT revealed mild uptake in all three patients, whereas (68)Ga-DOTATOC PET-CT revealed no significant uptake in any patient, making carcinoid tumor unlikely. Results of histopathological examination were consistent with low-grade mucoepidermoid carcinoma in all patients. CONCLUSION: Our study reveals that functional imaging may be helpful in the initial investigation of patients with mucoepidermoid carcinoma. (18)F-FDG PET-CT may have a prognostic relevance by predicting the histopathologic differentiation of the tumor. BioMed Central 2010-08-19 /pmc/articles/PMC2936317/ /pubmed/20723235 http://dx.doi.org/10.1186/1752-1947-4-277 Text en Copyright ©2010 Jindal et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Jindal, Tarun Kumar, Arvind Kumar, Rakesh Dutta, Roman Meena, Monika Role of positron emission tomography-computed tomography in bronchial mucoepidermoid carcinomas: a case series and review of the literature |
title | Role of positron emission tomography-computed tomography in bronchial mucoepidermoid carcinomas: a case series and review of the literature |
title_full | Role of positron emission tomography-computed tomography in bronchial mucoepidermoid carcinomas: a case series and review of the literature |
title_fullStr | Role of positron emission tomography-computed tomography in bronchial mucoepidermoid carcinomas: a case series and review of the literature |
title_full_unstemmed | Role of positron emission tomography-computed tomography in bronchial mucoepidermoid carcinomas: a case series and review of the literature |
title_short | Role of positron emission tomography-computed tomography in bronchial mucoepidermoid carcinomas: a case series and review of the literature |
title_sort | role of positron emission tomography-computed tomography in bronchial mucoepidermoid carcinomas: a case series and review of the literature |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936317/ https://www.ncbi.nlm.nih.gov/pubmed/20723235 http://dx.doi.org/10.1186/1752-1947-4-277 |
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