Cargando…

Thymostimulin versus placebo for palliative treatment of locally advanced or metastasised hepatocellular carcinoma: a phase III clinical trial

BACKGROUND: Thymostimulin is a thymic peptide fraction with immune-mediated cytotoxicity against hepatocellular carcinoma (HCC) in vitro and palliative efficacy in advanced HCC in two independent phase II trials. The aim of this study was to assess the efficacy of thymostimulin in a phase III trial....

Descripción completa

Detalles Bibliográficos
Autores principales:	Dollinger, Matthias M, Lautenschlaeger, Christine, Lesske, Joachim, Tannapfel, Andrea, Wagner, Anna-Dorothea, Schoppmeyer, Konrad, Nehls, Oliver, Welker, Martin-Walter, Wiest, Reiner, Fleig, Wolfgang E
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936330/ https://www.ncbi.nlm.nih.gov/pubmed/20735834 http://dx.doi.org/10.1186/1471-2407-10-457

Ejemplares similares

Thymostimulin in advanced hepatocellular carcinoma: A phase II trial
por: Dollinger, Matthias M, et al.
Publicado: (2008)

Discriminating metastasised from non-metastasised seminoma based on transcriptional changes in primary tumours using NGS
por: Ruf, C G, et al.
Publicado: (2014)

Breast cancer metastasising to the uterine cervix.
por: Bryson, C. A., et al.
Publicado: (1999)

Feline paraneoplastic alopecia associated with metastasising intestinal carcinoma
por: Grandt, Lisa-Maria, et al.
Publicado: (2015)

Supportive mistletoe therapy in a patient with metastasised neuroblastoma
por: Kaestner, Jens, et al.
Publicado: (2019)

Cellular senescence predicts treatment outcome in metastasised colorectal cancer
por: Haugstetter, A M, et al.
Publicado: (2010)

Extramedullary plasmacytoma of the oral cavity metastasising to both kidneys in a dog
por: Park, Kyung Ho, et al.
Publicado: (2023)

Metastasising ameloblastoma or ameloblastic carcinoma? A case report with mutation analyses
por: Hurník, Pavel, et al.
Publicado: (2023)

Rare case of hepatocellular carcinoma metastasising to the pituitary and cavernous sinus causing panhypopituitarism and bilateral ophthalmoplegia
por: Ambalavanan, Jayachidambaram, et al.
Publicado: (2020)

Intraosseous conventional central chondrosarcoma does not metastasise irrespective of grade in pelvis, scapula and in long bone locations
por: Laitinen, Minna K., et al.
Publicado: (2023)

The prognosis of primary and metastasising melanoma. An evaluation of the TNM classification in 2,495 patients.
por: Häffner, A. C., et al.
Publicado: (1992)

Oral anticoagulation in the treatment of a spontaneously metastasising murine tumour (3LL).
por: Hilgard, P., et al.
Publicado: (1977)

Adenoid cystic carcinoma of the lacrimal gland metastasising to the liver: report of a case
por: Zeidan, Bashar A, et al.
Publicado: (2006)

Tyrosine Kinase Inhibitors in the Treatment of Metastasised Renal Cell Carcinoma—Future or the Past?
por: Michaelis, Jakob, et al.
Publicado: (2022)

Gastric cancer with p53 overexpression has high potential for metastasising to lymph nodes.
por: Kakeji, Y., et al.
Publicado: (1993)

Squamous cell carcinoma of the uterine cervix metastasising to the thyroid gland: a case report
por: Ravindrakumar, Sanjeevan, et al.
Publicado: (2021)

A rare case of small-cell neuroendocrine tumour of the lung metastasising to the urinary bladder
por: Mapuranga, Humphrey, et al.
Publicado: (2023)

Isolation and properties of cell lines from the metastasising rat mammary tumour SMT-2A.
por: Rudland, P. S., et al.
Publicado: (1989)

A prolactin-dependent, metastasising rat mammary carcinoma as a model for endocrine-related tumour dormancy.
por: Wijsman, J. H., et al.
Publicado: (1991)

Epididymal papillary cystadenocarcinoma metastasising to the testis in a patient with infertility managed with Onco-microTeSE
por: Pindoria, Nisha, et al.
Publicado: (2016)

Percutaneous endoscopic gastrostomy – Too often? Too late? Who are the right patients for gastrostomy?
por: Dietrich, Christoph G, et al.
Publicado: (2020)

Heparanase is a prognostic indicator for postoperative survival in pancreatic carcinoma
por: Rohloff, J, et al.
Publicado: (2002)

Heparanase expression is a prognostic indicator for postoperative survival in pancreatic adenocarcinoma
por: Rohloff, J, et al.
Publicado: (2002)

The GALNT9, BNC1 and CCDC8 genes are frequently epigenetically dysregulated in breast tumours that metastasise to the brain
por: Pangeni, Rajendra P., et al.
Publicado: (2015)

Adenoid cystic carcinoma of the parotid metastasising to the dura fifteen years post primary resection: A case report
por: Bozkurt, Gulpembe, et al.
Publicado: (2020)

Genome-wide methylation analyses identifies Non-coding RNA genes dysregulated in breast tumours that metastasise to the brain
por: Pangeni, Rajendra P., et al.
Publicado: (2022)

Pulmonary Metastasising Aneurysmal Fibrous Histiocytoma: A Case Report, Literature Review and Proposal of Standardised Diagnostic Criteria
por: Mankertz, Fiona, et al.
Publicado: (2023)

Primary breast cancer stem-like cells metastasise to bone, switch phenotype and acquire a bone tropism signature
por: D′Amico, L, et al.
Publicado: (2013)

Differential Expression of Decorin in Metastasising Colorectal Carcinoma Is Regulated by miR-200c and Long Non-Coding RNAs
por: Žlajpah, Margareta, et al.
Publicado: (2022)

Rapid regression of neurological symptoms in patients with metastasised ALK+ lung cancer who are treated with lorlatinib: a report of two cases
por: Gafer, Huda, et al.
Publicado: (2019)

Metastasising Fibroblasts Show an HDAC6-Dependent Increase in Migration Speed and Loss of Directionality Linked to Major Changes in the Vimentin Interactome
por: Evans, Caroline A., et al.
Publicado: (2022)

Breast imaging surveillance after curative treatment for primary non-metastasised breast cancer in non-high-risk women: a systematic review
por: Swinnen, Jeroen, et al.
Publicado: (2018)

Time Trends in Treatment Strategies and Survival of Older versus Younger Patients with Synchronous Metastasised Melanoma—A Population-Based Study in the Netherlands Cancer Registry
por: van der Ziel, Daisy, et al.
Publicado: (2022)

In Vitro Ultrastructural Changes of MCF-7 for Metastasise Bone Cancer and Induction of Apoptosis via Mitochondrial Cytochrome C Released by CaCO(3)/Dox Nanocrystals
por: Shafiu Kamba, Abdullahi, et al.
Publicado: (2014)

Protocol to analyze transmigration of human cytotoxic T cells under physiological flow conditions in vitro
por: Schoppmeyer, Rouven, et al.
Publicado: (2022)

A Proof of Concept: Are Detection Dogs a Useful Tool to Verify Potential Biomarkers for Lung Cancer?
por: Fischer-Tenhagen, Carola, et al.
Publicado: (2018)

‘Palliative-D’—Vitamin D Supplementation to Palliative Cancer Patients: A Double Blind, Randomized Placebo-Controlled Multicenter Trial
por: Helde Frankling, Maria, et al.
Publicado: (2021)

Judicious usage of WHO Step III Opioids in Palliative Care in India
por: Ghoshal, Arunangshu
Publicado: (2020)

Palliative care stakeholders in Canada
por: Xiao, Jingjie, et al.
Publicado: (2022)

Successful Strategies and Areas of Improvement–Lessons Learned from Design and Conduction of a Randomized Placebo-Controlled Trial in Palliative Care, ‘Palliative-D’
por: Helde Frankling, Maria, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_egdrkj2no9l91ni722f9t921a9