The haematopoietic GTPase RhoH modulates IL3 signalling through regulation of STAT activity and IL3 receptor expression

BACKGROUND: RhoH is a constitutively active member of the family of Rho GTPases. Its expression is restricted to the haematopoietic lineage, where it serves as a positive regulator for T cell selection and mast cell function and as a negative regulator for growth-related functions in other lineages....

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Detalles Bibliográficos
Autores principales: Gündogdu, Mehtap S, Liu, He, Metzdorf, Daniela, Hildebrand, Dagmar, Aigner, Michael, Aktories, Klaus, Heeg, Klaus, Kubatzky, Katharina F
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936343/
https://www.ncbi.nlm.nih.gov/pubmed/20738848
http://dx.doi.org/10.1186/1476-4598-9-225

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