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Activation of voltage-gated KCNQ/Kv7 channels by anticonvulsant retigabine attenuates mechanical allodynia of inflammatory temporomandibular joint in rats

BACKGROUND: Temporomandibular disorders (TMDs) are characterized by persistent orofacial pain and have diverse etiologic factors that are not well understood. It is thought that central sensitization leads to neuronal hyperexcitability and contributes to hyperalgesia and spontaneous pain. Nonsteroid...

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Detalles Bibliográficos
Autores principales:	Xu, Wen, Wu, Yuwei, Bi, Yeping, Tan, Lei, Gan, Yehua, Wang, KeWei
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936374/ https://www.ncbi.nlm.nih.gov/pubmed/20796319 http://dx.doi.org/10.1186/1744-8069-6-49

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