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Decline in air pollution and change in prevalence in respiratory symptoms and chronic obstructive pulmonary disease in elderly women

BACKGROUND: While adverse effects of exposure to air pollutants on respiratory health are well studied, little is known about the effect of a reduction in air pollutants on chronic respiratory symptoms and diseases. We investigated whether different declines in air pollution levels in industrialised...

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Autores principales: Schikowski, Tamara, Ranft, Ulrich, Sugiri, Dorothee, Vierkötter, Andrea, Brüning, Thomas, Harth, Volker, Krämer, Ursula
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936381/
https://www.ncbi.nlm.nih.gov/pubmed/20727210
http://dx.doi.org/10.1186/1465-9921-11-113
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author Schikowski, Tamara
Ranft, Ulrich
Sugiri, Dorothee
Vierkötter, Andrea
Brüning, Thomas
Harth, Volker
Krämer, Ursula
author_facet Schikowski, Tamara
Ranft, Ulrich
Sugiri, Dorothee
Vierkötter, Andrea
Brüning, Thomas
Harth, Volker
Krämer, Ursula
author_sort Schikowski, Tamara
collection PubMed
description BACKGROUND: While adverse effects of exposure to air pollutants on respiratory health are well studied, little is known about the effect of a reduction in air pollutants on chronic respiratory symptoms and diseases. We investigated whether different declines in air pollution levels in industrialised and rural areas in Germany were associated with changes in respiratory health over a period of about 20 years. METHODS: We used data from the SALIA cohort study in Germany (Study on the influence of Air pollution on Lung function, Inflammation and Aging) to assess the association between the prevalence of chronic obstructive pulmonary disease (COPD) and chronic respiratory symptoms and the decline in air pollution exposure. In 1985-1994, 4874 women aged 55-years took part in the baseline investigation. Of these, 2116 participated in a questionnaire follow-up in 2006 and in a subgroup of 402 women lung function was tested in 2008-2009. Generalized estimating equation (GEE) models were used to estimate the effect of a reduction in air pollution on respiratory symptoms and diseases. RESULTS: Ambient air concentrations of particulate matter with aerodynamic size < 10 μm (PM(10)) declined in average by 20 μg/m(3). Prevalence of chronic cough with phlegm production and mild COPD at baseline investigation compared to follow-up was 9.5% vs. 13.3% and 8.6% vs. 18.2%, respectively. A steeper decline of PM(10 )was observed in the industrialized areas in comparison to the rural area, this was associated with a weaker increase in prevalence of respiratory symptoms and COPD. Among women who never smoked, the prevalence of chronic cough with phlegm and mild COPD was estimated at 21.4% and 39.5%, respectively, if no air pollution reduction was assumed, and at 13.3% and 17.5%, respectively, if air pollution reduction was assumed. CONCLUSION: We concluded that parallel to the decline of ambient air pollution over the last 20 years in the Ruhr area the age-related increase in chronic respiratory diseases and symptoms appears to attenuate in the population of elderly women.
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spelling pubmed-29363812011-07-08 Decline in air pollution and change in prevalence in respiratory symptoms and chronic obstructive pulmonary disease in elderly women Schikowski, Tamara Ranft, Ulrich Sugiri, Dorothee Vierkötter, Andrea Brüning, Thomas Harth, Volker Krämer, Ursula Respir Res Research BACKGROUND: While adverse effects of exposure to air pollutants on respiratory health are well studied, little is known about the effect of a reduction in air pollutants on chronic respiratory symptoms and diseases. We investigated whether different declines in air pollution levels in industrialised and rural areas in Germany were associated with changes in respiratory health over a period of about 20 years. METHODS: We used data from the SALIA cohort study in Germany (Study on the influence of Air pollution on Lung function, Inflammation and Aging) to assess the association between the prevalence of chronic obstructive pulmonary disease (COPD) and chronic respiratory symptoms and the decline in air pollution exposure. In 1985-1994, 4874 women aged 55-years took part in the baseline investigation. Of these, 2116 participated in a questionnaire follow-up in 2006 and in a subgroup of 402 women lung function was tested in 2008-2009. Generalized estimating equation (GEE) models were used to estimate the effect of a reduction in air pollution on respiratory symptoms and diseases. RESULTS: Ambient air concentrations of particulate matter with aerodynamic size < 10 μm (PM(10)) declined in average by 20 μg/m(3). Prevalence of chronic cough with phlegm production and mild COPD at baseline investigation compared to follow-up was 9.5% vs. 13.3% and 8.6% vs. 18.2%, respectively. A steeper decline of PM(10 )was observed in the industrialized areas in comparison to the rural area, this was associated with a weaker increase in prevalence of respiratory symptoms and COPD. Among women who never smoked, the prevalence of chronic cough with phlegm and mild COPD was estimated at 21.4% and 39.5%, respectively, if no air pollution reduction was assumed, and at 13.3% and 17.5%, respectively, if air pollution reduction was assumed. CONCLUSION: We concluded that parallel to the decline of ambient air pollution over the last 20 years in the Ruhr area the age-related increase in chronic respiratory diseases and symptoms appears to attenuate in the population of elderly women. BioMed Central 2010 2010-08-22 /pmc/articles/PMC2936381/ /pubmed/20727210 http://dx.doi.org/10.1186/1465-9921-11-113 Text en Copyright © 2010 Schikowski et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Schikowski, Tamara
Ranft, Ulrich
Sugiri, Dorothee
Vierkötter, Andrea
Brüning, Thomas
Harth, Volker
Krämer, Ursula
Decline in air pollution and change in prevalence in respiratory symptoms and chronic obstructive pulmonary disease in elderly women
title Decline in air pollution and change in prevalence in respiratory symptoms and chronic obstructive pulmonary disease in elderly women
title_full Decline in air pollution and change in prevalence in respiratory symptoms and chronic obstructive pulmonary disease in elderly women
title_fullStr Decline in air pollution and change in prevalence in respiratory symptoms and chronic obstructive pulmonary disease in elderly women
title_full_unstemmed Decline in air pollution and change in prevalence in respiratory symptoms and chronic obstructive pulmonary disease in elderly women
title_short Decline in air pollution and change in prevalence in respiratory symptoms and chronic obstructive pulmonary disease in elderly women
title_sort decline in air pollution and change in prevalence in respiratory symptoms and chronic obstructive pulmonary disease in elderly women
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936381/
https://www.ncbi.nlm.nih.gov/pubmed/20727210
http://dx.doi.org/10.1186/1465-9921-11-113
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