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A Single cis Element Maintains Repression of the Key Developmental Regulator Gata2
In development, lineage-restricted transcription factors simultaneously promote differentiation while repressing alternative fates. Molecular dissection of this process has been challenging as transcription factor loci are regulated by many trans-acting factors functioning through dispersed cis elem...
Autores principales: | Snow, Jonathan W., Trowbridge, Jennifer J., Fujiwara, Tohru, Emambokus, Nikla E., Grass, Jeffrey A., Orkin, Stuart H., Bresnick, Emery H. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936534/ https://www.ncbi.nlm.nih.gov/pubmed/20838598 http://dx.doi.org/10.1371/journal.pgen.1001103 |
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