High Content Phenotypic Cell-Based Visual Screen Identifies Mycobacterium tuberculosis Acyltrehalose-Containing Glycolipids Involved in Phagosome Remodeling

The ability of the tubercle bacillus to arrest phagosome maturation is considered one major mechanism that allows its survival within host macrophages. To identify mycobacterial genes involved in this process, we developed a high throughput phenotypic cell-based assay enabling individual sub-cellula...

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Detalles Bibliográficos
Autores principales: Brodin, Priscille, Poquet, Yannick, Levillain, Florence, Peguillet, Isabelle, Larrouy-Maumus, Gerald, Gilleron, Martine, Ewann, Fanny, Christophe, Thierry, Fenistein, Denis, Jang, Jichan, Jang, Mi-Seon, Park, Sei-Jin, Rauzier, Jean, Carralot, Jean-Philippe, Shrimpton, Rachel, Genovesio, Auguste, Gonzalo-Asensio, Jesus A., Puzo, Germain, Martin, Carlos, Brosch, Roland, Stewart, Graham R., Gicquel, Brigitte, Neyrolles, Olivier
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936551/
https://www.ncbi.nlm.nih.gov/pubmed/20844580
http://dx.doi.org/10.1371/journal.ppat.1001100

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