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Cyst formation in the PKD2 (1-703) transgenic rat precedes deregulation of proliferation-related pathways
BACKGROUND: Polycystic Kidney Disease is characterized by the formation of large fluid-filled cysts that eventually destroy the renal parenchyma leading to end-stage renal failure. Although remarkable progress has been made in understanding the pathologic mechanism of the disease, the precise orches...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936873/ https://www.ncbi.nlm.nih.gov/pubmed/20813037 http://dx.doi.org/10.1186/1471-2369-11-23 |