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Computing H/D-Exchange rates of single residues from data of proteolytic fragments

BACKGROUND: Protein conformation and protein/protein interaction can be elucidated by solution-phase Hydrogen/Deuterium exchange (sHDX) coupled to high-resolution mass analysis of the digested protein or protein complex. In sHDX experiments mutant proteins are compared to wild-type proteins or a lig...

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Detalles Bibliográficos
Autores principales:	Althaus, Ernst, Canzar, Stefan, Ehrler, Carsten, Emmett, Mark R, Karrenbauer, Andreas, Marshall, Alan G, Meyer-Bäse, Anke, Tipton, Jeremiah D, Zhang, Hui-Min
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936929/ https://www.ncbi.nlm.nih.gov/pubmed/20701784 http://dx.doi.org/10.1186/1471-2105-11-424

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