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Experimental observation of the improvement in MTF from backthinning a CMOS direct electron detector
The advantages of backthinning monolithic active pixel sensors (MAPS) based on complementary metal oxide semiconductor (CMOS) direct electron detectors for electron microscopy have been discussed previously; they include better spatial resolution (modulation transfer function or MTF) and efficiency...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2937214/ https://www.ncbi.nlm.nih.gov/pubmed/19541421 http://dx.doi.org/10.1016/j.ultramic.2009.05.005 |
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author | McMullan, G. Faruqi, A.R. Henderson, R. Guerrini, N. Turchetta, R. Jacobs, A. van Hoften, G. |
author_facet | McMullan, G. Faruqi, A.R. Henderson, R. Guerrini, N. Turchetta, R. Jacobs, A. van Hoften, G. |
author_sort | McMullan, G. |
collection | PubMed |
description | The advantages of backthinning monolithic active pixel sensors (MAPS) based on complementary metal oxide semiconductor (CMOS) direct electron detectors for electron microscopy have been discussed previously; they include better spatial resolution (modulation transfer function or MTF) and efficiency at all spatial frequencies (detective quantum efficiency or DQE). It was suggested that a ‘thin’ CMOS detector would have the most outstanding properties [1–3] because of a reduction in the proportion of backscattered electrons. In this paper we show, theoretically (using Monte Carlo simulations of electron trajectories) and experimentally that this is indeed the case. The modulation transfer functions of prototype backthinned CMOS direct electron detectors have been measured at 300 keV. At zero spatial frequency, in non-backthinned 700-μm-thick detectors, the backscattered component makes up over 40% of the total signal but, by backthinning to 100, 50 or 35 μm, this can be reduced to 25%, 15% and 10%, respectively. For the 35 μm backthinned detector, this reduction in backscatter increases the MTF by 40% for spatial frequencies between 0.1 and 1.0 Nyquist. As discussed in the main text, reducing backscattering in backthinned detectors should also improve DQE. |
format | Text |
id | pubmed-2937214 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-29372142010-10-13 Experimental observation of the improvement in MTF from backthinning a CMOS direct electron detector McMullan, G. Faruqi, A.R. Henderson, R. Guerrini, N. Turchetta, R. Jacobs, A. van Hoften, G. Ultramicroscopy Article The advantages of backthinning monolithic active pixel sensors (MAPS) based on complementary metal oxide semiconductor (CMOS) direct electron detectors for electron microscopy have been discussed previously; they include better spatial resolution (modulation transfer function or MTF) and efficiency at all spatial frequencies (detective quantum efficiency or DQE). It was suggested that a ‘thin’ CMOS detector would have the most outstanding properties [1–3] because of a reduction in the proportion of backscattered electrons. In this paper we show, theoretically (using Monte Carlo simulations of electron trajectories) and experimentally that this is indeed the case. The modulation transfer functions of prototype backthinned CMOS direct electron detectors have been measured at 300 keV. At zero spatial frequency, in non-backthinned 700-μm-thick detectors, the backscattered component makes up over 40% of the total signal but, by backthinning to 100, 50 or 35 μm, this can be reduced to 25%, 15% and 10%, respectively. For the 35 μm backthinned detector, this reduction in backscatter increases the MTF by 40% for spatial frequencies between 0.1 and 1.0 Nyquist. As discussed in the main text, reducing backscattering in backthinned detectors should also improve DQE. Elsevier 2009-08 /pmc/articles/PMC2937214/ /pubmed/19541421 http://dx.doi.org/10.1016/j.ultramic.2009.05.005 Text en © 2009 Elsevier B.V. https://creativecommons.org/licenses/by/3.0/ Open Access under CC BY 3.0 (https://creativecommons.org/licenses/by/3.0/) license |
spellingShingle | Article McMullan, G. Faruqi, A.R. Henderson, R. Guerrini, N. Turchetta, R. Jacobs, A. van Hoften, G. Experimental observation of the improvement in MTF from backthinning a CMOS direct electron detector |
title | Experimental observation of the improvement in MTF from backthinning a CMOS direct electron detector |
title_full | Experimental observation of the improvement in MTF from backthinning a CMOS direct electron detector |
title_fullStr | Experimental observation of the improvement in MTF from backthinning a CMOS direct electron detector |
title_full_unstemmed | Experimental observation of the improvement in MTF from backthinning a CMOS direct electron detector |
title_short | Experimental observation of the improvement in MTF from backthinning a CMOS direct electron detector |
title_sort | experimental observation of the improvement in mtf from backthinning a cmos direct electron detector |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2937214/ https://www.ncbi.nlm.nih.gov/pubmed/19541421 http://dx.doi.org/10.1016/j.ultramic.2009.05.005 |
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