Zidovudine-induced reversible pure red cell aplasia

Hematological abnormalities are frequent among human immunodeficiency virus (HIV)-infected patients and may be directly attributable to the virus or may be caused by opportunistic infections, neoplasms or drugs that cause bone marrow suppression or hemolysis. Pure red cell aplasia (PRCA) is an uncom...

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Autores principales: Balakrishnan, Anuja, Valsalan, Rohith, Sheshadri, Shubha, Pandit, Vinay R., Medep, Vikas, Agrawal, Ravindra Kumar
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2010
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2937323/
https://www.ncbi.nlm.nih.gov/pubmed/20871773
http://dx.doi.org/10.4103/0253-7613.66845
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author Balakrishnan, Anuja
Valsalan, Rohith
Sheshadri, Shubha
Pandit, Vinay R.
Medep, Vikas
Agrawal, Ravindra Kumar
author_facet Balakrishnan, Anuja
Valsalan, Rohith
Sheshadri, Shubha
Pandit, Vinay R.
Medep, Vikas
Agrawal, Ravindra Kumar
author_sort Balakrishnan, Anuja
collection PubMed
description Hematological abnormalities are frequent among human immunodeficiency virus (HIV)-infected patients and may be directly attributable to the virus or may be caused by opportunistic infections, neoplasms or drugs that cause bone marrow suppression or hemolysis. Pure red cell aplasia (PRCA) is an uncommon hematological disorder that causes anemia. We report a 37-year-old male with HIV infection who developed PRCA 6 weeks after commencing Zidovudine and recovered following cessation of the drug. This is the first case of Zidovudine-induced PRCA reported from the Indian subcontinent.
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spelling pubmed-29373232010-09-24 Zidovudine-induced reversible pure red cell aplasia Balakrishnan, Anuja Valsalan, Rohith Sheshadri, Shubha Pandit, Vinay R. Medep, Vikas Agrawal, Ravindra Kumar Indian J Pharmacol Case Report Hematological abnormalities are frequent among human immunodeficiency virus (HIV)-infected patients and may be directly attributable to the virus or may be caused by opportunistic infections, neoplasms or drugs that cause bone marrow suppression or hemolysis. Pure red cell aplasia (PRCA) is an uncommon hematological disorder that causes anemia. We report a 37-year-old male with HIV infection who developed PRCA 6 weeks after commencing Zidovudine and recovered following cessation of the drug. This is the first case of Zidovudine-induced PRCA reported from the Indian subcontinent. Medknow Publications 2010-06 /pmc/articles/PMC2937323/ /pubmed/20871773 http://dx.doi.org/10.4103/0253-7613.66845 Text en © Indian Journal of Pharmacology http://creativecommons.org/licenses/by/2.0 This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Balakrishnan, Anuja
Valsalan, Rohith
Sheshadri, Shubha
Pandit, Vinay R.
Medep, Vikas
Agrawal, Ravindra Kumar
Zidovudine-induced reversible pure red cell aplasia
title Zidovudine-induced reversible pure red cell aplasia
title_full Zidovudine-induced reversible pure red cell aplasia
title_fullStr Zidovudine-induced reversible pure red cell aplasia
title_full_unstemmed Zidovudine-induced reversible pure red cell aplasia
title_short Zidovudine-induced reversible pure red cell aplasia
title_sort zidovudine-induced reversible pure red cell aplasia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2937323/
https://www.ncbi.nlm.nih.gov/pubmed/20871773
http://dx.doi.org/10.4103/0253-7613.66845
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