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Networks Inferred from Biochemical Data Reveal Profound Differences in Toll-like Receptor and Inflammatory Signaling between Normal and Transformed Hepatocytes
Systematic study of cell signaling networks increasingly involves high throughput proteomics, transcriptional profiling, and automated literature mining with the aim of assembling large scale interaction networks. In contrast, functional analysis of cell signaling usually focuses on a much smaller s...
Autores principales: | Alexopoulos, Leonidas G., Saez-Rodriguez, Julio, Cosgrove, Benjamin D., Lauffenburger, Douglas A., Sorger, Peter K. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The American Society for Biochemistry and Molecular Biology
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938121/ https://www.ncbi.nlm.nih.gov/pubmed/20460255 http://dx.doi.org/10.1074/mcp.M110.000406 |
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